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  Emotional Health

Antidepressants: Don't let side effects get you down

Now that you've started taking medication to treat your depression, are you feeling worse than you were before? Were you expecting that your antidepressant would whisk away the symptoms of depression overnight, but instead, you're feeling so nauseous and tired that you can't see straight? Or is that blurred vision actually yet another side effect?

If you've recently started taking antidepressants, the physical effects that come along with it may be enough to make you feel even more depressed. But there is good news. Though there are a number of unpleasant side effects associated with using antidepressants, most are mild and most are temporary.

While researchers don't know exactly how antidepressants work to ease the symptoms of depression, they do know these medications affect brain chemistry by changing the levels of neurotransmitters - chemicals which nerve cells in the brain use to communicate - that are associated with mood. In particular, there are three types of neurotransmitters associated with depression - serotonin, norepinephrine and possibly dopamine - and it is believed people suffering with depression have decreased levels of at least one of the three.

There are many antidepressants available by prescription, and they can affect neurotransmitters by different mechanisms. While most have a similar level of effectiveness, it may take 2-4 weeks to see positive effects.

Unfortunately, during that time, you may also experience a number of side effects, including:

  • blurred vision
  • constipation
  • dizziness
  • dry mouth
  • fatigue
  • feeling agitated and anxious
  • increased appetite or weight gain
  • insomnia
  • low sex drive

These effects may vary from person to person. But before you let them get you down (or consider stop taking your meds), you should know that the side effects associated with antidepressants tend to be most pronounced at the beginning of treatment and then ease.

Until then, there are ways you can manage these effects.

Nausea, a common side effect, typically goes away on its own within a few weeks of starting on antidepressants. But because this feeling can be so intolerable, it is one of the most common reasons why people tend to stop taking their medication. Like other side effects, this feeling can be minimized: Make sure to always take your medication with food and consider taking an antacid or bismuth subsalicylate to ease stomach irritation. If nausea persists, you may also want to talk to your doctor or pharmacist about a slow-release form of your antidepressant or a dosage change.

Eating a well-balanced diet with lots of fruit, vegetables and whole grains and drinking plenty of water can help you keep weight off and ease constipation. As well, regular exercise will not only help you manage those two issues, but a mild workout can also keep you more alert during the day, ease anxiety and help fight insomnia. If you suffer from anxiety, insomnia or dizziness, it's a good idea to limit your intake of foods and beverages that contain caffeine.

Dry mouth is common in people who use antidepressants that block the action of the neurotransmitter acetylcholine, but there are a number of things that can help restore moisture. If this is a problem, sip water or suck on ice chips throughout the day and chew sugarless gum or suck on sugarless candy to promote extra saliva. You should also try to breathe through your noise rather than your mouth.

Keep track of your side effects and speak to your doctor as some may require a dose adjustment or switching to another medication to help. For example, if you are experiencing insomnia, your doctor may prescribe a mild sedative to take at bedtime. If blurred vision is a problem, you may want to get an eye exam to rule out other problems, or your doctor or pharmacist may be able to recommend eye drops that can relieve dryness.

As well, some antidepressants have been more closely linked to some side effects than others. For example, bupropion and certain selective serotonin reuptake inhibitors (SSRIs) are less likely to cause weight gain. Bupropion and mirtazapine are also less likely to have sexual side effects.

So pay close attention to how your antidepressant makes you feel. Not only will side effects vary from person to person, but so will a drug's effectiveness. If after six to eight weeks, your side effects aren't easing or you don't feel less depressed than before you started your medication, you may want to talk to your doctor about trying a different antidepressant.

But you should never stop taking your antidepressants or change your dosage without talking to your doctor first. Some antidepressants may cause serious withdrawal symptoms and other effects if you stop taking them abruptly.

Just remember: you chose to go on antidepressants so you would feel better. And with some strategies for managing your side effects, and communication with your doctor and pharmacist if any issues arise, you soon should feel better!

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